MOVING BEYOND RANDOMIZED CONTROLLED TRIALS
نویسندگان
چکیده
منابع مشابه
Blindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملMoving forward with randomized controlled trials.
A randomized controlled trial (RCT) is the most powerful tool for determining the cause-effect relationship between an intervention and an outcome. RCTs typically include random allocation to intervention and control groups, a blinding plan for trialists, assessors and/or participants, identical treatment groups except for the experimental ingredients, and an intent-to-treat analysis. RCTs are ...
متن کاملEvidence-based public health: moving beyond randomized trials.
Randomized controlled trials (RCTs) are essential for evaluating the efficacy of clinical interventions, where the causal chain between the agent and the outcome is relatively short and simple and where results may be safely extrapolated to other settings. However, causal chains in public health interventions are complex, making RCT results subject to effect modification in different population...
متن کاملObservational studies: going beyond the boundaries of randomized controlled trials.
The term observational study describes a wide range of study designs including prospective and retrospective cohort studies, case-control studies, and cross-sectional studies, a defining feature of which is that any intervention studied is determined by clinical practice and not the protocol. Data from large, prospective observational studies provide information about the safety and efficacy of...
متن کاملQigong and Fibromyalgia: Randomized Controlled Trials and Beyond
Introduction. Qigong is currently considered as meditative movement, mindful exercise, or complementary exercise and is being explored for relief of symptoms in fibromyalgia. Aim. This narrative review summarizes randomized controlled trials, as well as additional studies, of qigong published to the end of 2013 and discusses relevant methodological issues. Results. Controlled trials indicate re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Public Health
سال: 2004
ISSN: 0090-0036,1541-0048
DOI: 10.2105/ajph.94.9.1476